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T-Coffee

T-Coffee (Tree based Consistency Objective Function For Alignment Evaluation) is a tool for multiple sequence alignment (Notredame et al. 2000). T-Coffee can combine separate alignments generated within T-Coffee or from other alignment software into a single alignment. This program also gives a consistency score for each position of a combined alignment which can indicate the accuracy of the new alignment.

Version 5.72

Input data file format

FASTA

Instructions

To run T-Coffee from a UNIX shell type:

t_coffee input > output

at the command prompt of the terminal window.

A T-Coffee tutorial is available. Another tutorial is also available from Steve Thompson.

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Maintained by Adam Bazinet
Direct questions and comments to Michael Cummings